This compound provides the vital biphenyl structure, enabling the creation of these widely used cardiovascular medications. 4′-(Bromomethyl)-2-cyanobiphenyl (Br-OTBN) is a crucial intermediate for synthesizing the sartan class of drugs, which are Angiotensin II Receptor Blockers (ARBs) used to treat hypertension and heart failure, including APIs like Losartan, Valsartan, Telmisartan, and Azilsartan.
4′-(Bromomethyl)-2-cyanobiphenyl
| API Name | Valsartan |
|---|---|
| CAS No | 114772-54-2 |
| Molecular Formula | C14H10BrN |
| Molecular Weight | 272.14 g/mol |
| Synonyms | 2-[4-(bromomethyl)phenyl]benzonitrile |
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Frequently Asked Questions
This compound provides the vital biphenyl structure, enabling the creation of these widely used cardiovascular medications. 4'-(Bromomethyl)-2-cyanobiphenyl (Br-OTBN) is a crucial intermediate for synthesizing the sartan class of drugs, which are Angiotensin II Receptor Blockers (ARBs) used to treat hypertension and heart failure, including APIs like Losartan, Valsartan, Telmisartan, and Azilsartan.
The CAS number of 4′-(Bromomethyl)-2-cyanobiphenyl is 114772-54-2.
The molecular formula of 4′-(Bromomethyl)-2-cyanobiphenyl is C14H10BrN.
The listed molecular weight of 4′-(Bromomethyl)-2-cyanobiphenyl is 272.14 g/mol.
4′-(Bromomethyl)-2-cyanobiphenyl is listed as being used in connection with the following API: Valsartan.
The listed synonym or IUPAC name for 4′-(Bromomethyl)-2-cyanobiphenyl is 2-[4-(bromomethyl)phenyl]benzonitrile.