(3R,4S,5R,6R)-3,4,5-Tris-trimethylsilanyloxy-6-trimethylsilanyloxymethyl-tetrahydro-pyran-2-on

This compound is a heavily protected chiral carbohydrate-derived lactone, used strictly as a synthetic intermediate. Structurally, it is a tetrahydropyran-2-one (lactone) ring bearing four trimethylsilyl (TMS)–protected hydroxyl groups, with defined stereochemistry at four contiguous chiral centers (3R,4S,5R,6R). The directory classifies it as a under development API with a synthetic source/manufacturing origin. Other names for this substance include 2, 3, 4, 6-tetrakis-o-trimethylsilyl-d-gluconolactone and Canagliflozin Impurity 34. It is also listed for alternate use as: API Intermediate. Its PubChem CID is 10994280.

CAS No 32384-65-9
Molecular Formula C18H42O6Si4
Molecular Weight 466.9 g/mol
Synonyms (3R,4S,5R,6R)-3,4,5-tris(trimethylsilyloxy)-6-(trimethylsilyloxymethyl)oxan-2-one

Frequently Asked Questions