It serves as the precursor to the chiral piperidine core, in which the N-benzyl group is removed via hydrogenation to allow N-acylation, providing the 3-aminopiperidine moiety essential for Tofacitinib’s structure. 3-Piperidinamine, N,4-dimethyl-1-(phenylmethyl)-, hydrochloride (1:2) acts as a critical intermediate in the synthesis of Tofacitinib.
3-Piperidinamine, N,4-dimethyl-1-(phenylmethyl)-, hydrochloride (1:2)
| API Name | Tofacitinib |
|---|---|
| CAS No | 1228879-37-5 |
| Molecular Formula | C14H24Cl2N2 |
| Molecular Weight | 291.3 g/mol |
| Synonyms | 1-benzyl-N,4-dimethylpiperidin-3-amine;dihydrochloride |
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Frequently Asked Questions
It serves as the precursor to the chiral piperidine core, in which the N-benzyl group is removed via hydrogenation to allow N-acylation, providing the 3-aminopiperidine moiety essential for Tofacitinib's structure. 3-Piperidinamine, N,4-dimethyl-1-(phenylmethyl)-, hydrochloride (1:2) acts as a critical intermediate in the synthesis of Tofacitinib.
The CAS number of 3-Piperidinamine, N,4-dimethyl-1-(phenylmethyl)-, hydrochloride (1:2) is 1228879-37-5.
The molecular formula of 3-Piperidinamine, N,4-dimethyl-1-(phenylmethyl)-, hydrochloride (1:2) is C14H24Cl2N2.
The listed molecular weight of 3-Piperidinamine, N,4-dimethyl-1-(phenylmethyl)-, hydrochloride (1:2) is 291.3 g/mol.
3-Piperidinamine, N,4-dimethyl-1-(phenylmethyl)-, hydrochloride (1:2) is listed as being used in connection with the following API: Tofacitinib.
The listed synonym or IUPAC name for 3-Piperidinamine, N,4-dimethyl-1-(phenylmethyl)-, hydrochloride (1:2) is 1-benzyl-N,4-dimethylpiperidin-3-amine;dihydrochloride.