3-Methyl-6-nitro-1H-indazole

It serves as the precursor to 2,3-dimethyl-6-nitro-2H-indazole (a key intermediate) through methylation, followed by reduction to form the essential indazole core of the final drug molecule. 3-Methyl-6-nitro-1H-indazole is a vital starting material in the industrial synthesis of Pazopanib, a tyrosine kinase inhibitor for cancer treatment.

API Name Pazopanib
CAS No 6494-19-5
Molecular Formula C8H7N3O2
Molecular Weight 177.16 g/mol
Synonyms 3-methyl-6-nitro-2H-indazole