This coupling connects the hydroxymethyl-substituted phenyl ring to the pyrimidine, setting up the structure for subsequent etherification and other reactions needed to complete the Pacritinib molecule. [3-(Hydroxymethyl)phenyl]boronic acid is a key building block in synthesizing Pacritinib, mainly used in a Suzuki-Miyaura coupling reaction with a pyrimidine derivative (like 2,4-dichloropyrimidine) to form a crucial intermediate, establishing the phenyl-pyrimidine core of the drug.
[3-(Hydroxymethyl)phenyl]boronic acid
| API Name | Pacritinib |
|---|---|
| CAS No | 87199-15-3 |
| Molecular Formula | C7H9BO3 |
| Molecular Weight | 151.96 g/mol |
| Synonyms | [3-(hydroxymethyl)phenyl]boronic acid |
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Frequently Asked Questions
This coupling connects the hydroxymethyl-substituted phenyl ring to the pyrimidine, setting up the structure for subsequent etherification and other reactions needed to complete the Pacritinib molecule. [3-(Hydroxymethyl)phenyl]boronic acid is a key building block in synthesizing Pacritinib, mainly used in a Suzuki-Miyaura coupling reaction with a pyrimidine derivative (like 2,4-dichloropyrimidine) to form a crucial intermediate, establishing the phenyl-pyrimidine core of the drug.
The CAS number of [3-(Hydroxymethyl)phenyl]boronic acid is 87199-15-3.
The molecular formula of [3-(Hydroxymethyl)phenyl]boronic acid is C7H9BO3.
The listed molecular weight of [3-(Hydroxymethyl)phenyl]boronic acid is 151.96 g/mol.
[3-(Hydroxymethyl)phenyl]boronic acid is listed as being used in connection with the following API: Pacritinib.
The listed synonym or IUPAC name for [3-(Hydroxymethyl)phenyl]boronic acid is [3-(hydroxymethyl)phenyl]boronic acid.