3-Bromo-1-phenyl-5-(pyridin-2-yl)-1,2-dihydropyridin-2-one

It serves as a precursor to the final bipyridine core, in which the 3-bromo group is typically substituted with a 2-cyanophenyl group via Suzuki-Miyaura coupling. 3-Bromo-1-phenyl-5-(pyridin-2-yl)-1,2-dihydropyridin-2-one is a key advanced intermediate in the synthesis of the antiepileptic drug Perampanel.

API Name Perampanel
CAS No 381248-06-2
Molecular Formula C16H11BrN2O
Molecular Weight 327.17 g/mol
Synonyms 3-bromo-1-phenyl-5-pyridin-2-ylpyridin-2-one

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