3-amino-N-(tert-butyl)benzenesulfonamide

This intermediate provides the sulfonamide moiety, often coupled with a pyrimidine core via Buchwald-Hartwig amination. It acts as a critical precursor for the final drug structure. 3-amino-N-(tert-butyl)benzenesulfonamide is a key building block in the synthesis of Fedratinib, a JAK2 inhibitor used for myelofibrosis.