This intermediate provides the sulfonamide moiety, often coupled with a pyrimidine core via Buchwald-Hartwig amination. It acts as a critical precursor for the final drug structure. 3-amino-N-(tert-butyl)benzenesulfonamide is a key building block in the synthesis of Fedratinib, a JAK2 inhibitor used for myelofibrosis.
3-amino-N-(tert-butyl)benzenesulfonamide
| API Name | Fedratinib |
|---|---|
| CAS No | 608523-94-0 |
| Molecular Formula | C10H16N2O2S |
| Molecular Weight | 228.31 g/mol |
| Synonyms | 3-amino-N-tert-butylbenzenesulfonamide |
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Frequently Asked Questions
This intermediate provides the sulfonamide moiety, often coupled with a pyrimidine core via Buchwald-Hartwig amination. It acts as a critical precursor for the final drug structure. 3-amino-N-(tert-butyl)benzenesulfonamide is a key building block in the synthesis of Fedratinib, a JAK2 inhibitor used for myelofibrosis.
The CAS number of 3-amino-N-(tert-butyl)benzenesulfonamide is 608523-94-0.
The molecular formula of 3-amino-N-(tert-butyl)benzenesulfonamide is C10H16N2O2S.
The listed molecular weight of 3-amino-N-(tert-butyl)benzenesulfonamide is 228.31 g/mol.
3-amino-N-(tert-butyl)benzenesulfonamide is listed as being used in connection with the following API: Fedratinib.
The listed synonym or IUPAC name for 3-amino-N-(tert-butyl)benzenesulfonamide is 3-amino-N-tert-butylbenzenesulfonamide.