3-Amino-1-(3-(trifluoromethyl)-5,6-dihydro(1,2,4)triazolo(4,3-a)pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one

It is a dipeptidyl peptidase-4 (DPP-IV) inhibitor that works by helping the body release more insulin and reducing the production of glucagon. The chemical name “3-Amino-1-(3-(trifluoromethyl)-5,6-dihydro(1,2,4)triazolo(4,3-a)pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one” is the active pharmaceutical ingredient in the type 2 diabetes medication sitagliptin.

API Name Sitagliptin
CAS No 823817-56-7
Molecular Formula C16H15F6N5O
Molecular Weight 407.31 g/mol
Synonyms 3-amino-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one

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