3-(1-(Dimethylamino)ethyl)phenol hydrochloride

It provides the phenolic and dimethylamino functional groups necessary for subsequent carbamate formation, allowing coupling with the appropriate carbamoylating agent to produce rivastigmine. Essentially, it acts as the nucleophilic phenol building block in the preparation of the active drug. 3-(1-(Dimethylamino)ethyl)phenol hydrochloride is a key intermediate in the synthesis of Rivastigmine Tartrate, a cholinesterase inhibitor used for Alzheimer’s disease.

API Name Rivastigmine tartrate
CAS No 5441-61-2
Molecular Formula C10H16ClNO
Molecular Weight 201.69 g/mol
Synonyms 3-[1-(dimethylamino)ethyl]phenol;hydrochloride