It is a chiral β-amino-α-hydroxy ester bearing a para-methylsulfonyl phenyl substituent, a motif frequently employed to enhance polarity, metabolic stability, and target binding in medicinal chemistry programs. (2R,3S)-Ethyl 2-amino-3-hydroxy-3-(4-(methylsulfonyl)phenyl)propanoate is a stereochemically defined pharmaceutical intermediate employed to synthesize complex small-molecule drug candidates.
(2R,3S)-Ethyl 2-amino-3-hydroxy-3-(4-(methylsulfonyl)phenyl)propanoate
| API Name | Sacubitril |
|---|---|
| CAS No | 36983-12-7 |
| Molecular Formula | C12H17NO5S |
| Molecular Weight | 287.33 g/mol |
| Synonyms | ethyl (2R,3S)-2-amino-3-hydroxy-3-(4-methylsulfonylphenyl)propanoate |
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Frequently Asked Questions
It is a chiral β-amino-α-hydroxy ester bearing a para-methylsulfonyl phenyl substituent, a motif frequently employed to enhance polarity, metabolic stability, and target binding in medicinal chemistry programs. (2R,3S)-Ethyl 2-amino-3-hydroxy-3-(4-(methylsulfonyl)phenyl)propanoate is a stereochemically defined pharmaceutical intermediate employed to synthesize complex small-molecule drug candidates.
The CAS number of (2R,3S)-Ethyl 2-amino-3-hydroxy-3-(4-(methylsulfonyl)phenyl)propanoate is 36983-12-7.
The molecular formula of (2R,3S)-Ethyl 2-amino-3-hydroxy-3-(4-(methylsulfonyl)phenyl)propanoate is C12H17NO5S.
The listed molecular weight of (2R,3S)-Ethyl 2-amino-3-hydroxy-3-(4-(methylsulfonyl)phenyl)propanoate is 287.33 g/mol.
(2R,3S)-Ethyl 2-amino-3-hydroxy-3-(4-(methylsulfonyl)phenyl)propanoate is listed as being used in connection with the following API: Sacubitril.
The listed synonym or IUPAC name for (2R,3S)-Ethyl 2-amino-3-hydroxy-3-(4-(methylsulfonyl)phenyl)propanoate is ethyl (2R,3S)-2-amino-3-hydroxy-3-(4-methylsulfonylphenyl)propanoate.