It often serves to produce the 6-fluoro-3,4-dihydro-2H-1-benzopyran-2-carboxaldehyde, which is subsequently converted into the oxirane intermediate essential for forming the final, complex molecule of Nebivolol. Ethyl 6-fluoro-3,4-dihydro-2H-1-benzopyran-2-carboxylate is a critical key intermediate used in the industrial synthesis of Nebivolol, a third-generation selective beta1-blocker.
2H-1-Benzopyran-2-carboxylic acid, 6-fluoro-3,4-dihydro-, ethyl ester
| API Name | Nebivolol |
|---|---|
| CAS No | 99199-61-8 |
| Molecular Formula | C12H13FO3 |
| Molecular Weight | 224.23 g/mol |
| Synonyms | ethyl 6-fluoro-3,4-dihydro-2H-chromene-2-carboxylate |
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