The molecule contains a defined E-alkene (2E) and a single stereogenic center (4R), ensuring controlled geometry and stereochemistry during downstream synthesis. Its biphenyl aromatic moiety contributes significant hydrophobic character, while the Boc-protected amine enables selective transformations and can be cleanly deprotected under mild acidic conditions. (2E,4R)-5-(1,1′-Biphenyl)-4-yl-4-(((1,1-dimethylethoxy)carbonyl)amino)-2-methyl-2-pentenoic acid is a chiral, Boc-protected amino acid derivative used exclusively as a synthetic intermediate in medicinal and fine chemical research.
(2E,4R)-5-(1,1′-Biphenyl)-4-yl-4-(((1,1-dimethylethoxy)carbonyl)amino)-2-methyl-2-pentenoic acid
| API Name | Sacubitril |
|---|---|
| CAS No | 1012341-48-8 |
| Molecular Formula | C23H27NO4 |
| Molecular Weight | 381.5 g/mol |
| Synonyms | (E,4R)-2-methyl-4-[(2-methylpropan-2-yl)oxycarbonylamino]-5-(4-phenylphenyl)pent-2-enoic acid |
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Frequently Asked Questions
The molecule contains a defined E-alkene (2E) and a single stereogenic center (4R), ensuring controlled geometry and stereochemistry during downstream synthesis. Its biphenyl aromatic moiety contributes significant hydrophobic character, while the Boc-protected amine enables selective transformations and can be cleanly deprotected under mild acidic conditions. (2E,4R)-5-(1,1′-Biphenyl)-4-yl-4-(((1,1-dimethylethoxy)carbonyl)amino)-2-methyl-2-pentenoic acid is a chiral, Boc-protected amino acid derivative used exclusively as a synthetic intermediate in medicinal and fine chemical research.
The CAS number of (2E,4R)-5-(1,1′-Biphenyl)-4-yl-4-(((1,1-dimethylethoxy)carbonyl)amino)-2-methyl-2-pentenoic acid is 1012341-48-8.
The molecular formula of (2E,4R)-5-(1,1′-Biphenyl)-4-yl-4-(((1,1-dimethylethoxy)carbonyl)amino)-2-methyl-2-pentenoic acid is C23H27NO4.
The listed molecular weight of (2E,4R)-5-(1,1′-Biphenyl)-4-yl-4-(((1,1-dimethylethoxy)carbonyl)amino)-2-methyl-2-pentenoic acid is 381.5 g/mol.
(2E,4R)-5-(1,1′-Biphenyl)-4-yl-4-(((1,1-dimethylethoxy)carbonyl)amino)-2-methyl-2-pentenoic acid is listed as being used in connection with the following API: Sacubitril.
The listed synonym or IUPAC name for (2E,4R)-5-(1,1′-Biphenyl)-4-yl-4-(((1,1-dimethylethoxy)carbonyl)amino)-2-methyl-2-pentenoic acid is (E,4R)-2-methyl-4-[(2-methylpropan-2-yl)oxycarbonylamino]-5-(4-phenylphenyl)pent-2-enoic acid.