It is produced by acetylating guanine with acetic anhydride, then alkylated with (2-acetoxyethoxy)methyl chloride and hydrolyzed to produce Acyclovir. 2,9-Diacetylguanine (DAG) is a key protected intermediate employed to synthesize the antiviral drug Acyclovir to improve yield and regioselectivity (ensuring N-9 isomer formation over N-7).
2,9-Diacetylguanine
| API Name | Acyclovir |
|---|---|
| CAS No | 3056-33-5 |
| Molecular Formula | C9H9N5O3 |
| Molecular Weight | 235.20 g/mol |
| Synonyms | N-(9-acetyl-6-oxo-1H-purin-2-yl)acetamide |
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Frequently Asked Questions
It is produced by acetylating guanine with acetic anhydride, then alkylated with (2-acetoxyethoxy)methyl chloride and hydrolyzed to produce Acyclovir. 2,9-Diacetylguanine (DAG) is a key protected intermediate employed to synthesize the antiviral drug Acyclovir to improve yield and regioselectivity (ensuring N-9 isomer formation over N-7).
The CAS number of 2,9-Diacetylguanine is 3056-33-5.
The molecular formula of 2,9-Diacetylguanine is C9H9N5O3.
The listed molecular weight of 2,9-Diacetylguanine is 235.20 g/mol.
2,9-Diacetylguanine is listed as being used in connection with the following API: Acyclovir.
The listed synonym or IUPAC name for 2,9-Diacetylguanine is N-(9-acetyl-6-oxo-1H-purin-2-yl)acetamide.