This key intermediate introduces the characteristic difluorobenzyl moiety, essential for Rufinamide’s therapeutic action in treating Lennox-Gastaut syndrome seizures. 2,6-Difluorobenzyl chloride is a crucial starting material for synthesizing Rufinamide, an anticonvulsant drug, serving as the source for the difluorobenzyl group, typically converted to 2,6-difluorobenzyl azide which then undergoes cycloaddition with an alkyne (like propiolic acid derivatives) to form the 1,2,3-triazole ring core of Rufinamide through Click chemistry.
2,6-Difluorobenzyl chloride
| API Name | Rufinamide |
|---|---|
| CAS No | 697-73-4 |
| Molecular Formula | C7H5ClF2 |
| Molecular Weight | 162.56 g/mol |
| Synonyms | 2-(chloromethyl)-1,3-difluorobenzene |
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Frequently Asked Questions
This key intermediate introduces the characteristic difluorobenzyl moiety, essential for Rufinamide's therapeutic action in treating Lennox-Gastaut syndrome seizures. 2,6-Difluorobenzyl chloride is a crucial starting material for synthesizing Rufinamide, an anticonvulsant drug, serving as the source for the difluorobenzyl group, typically converted to 2,6-difluorobenzyl azide which then undergoes cycloaddition with an alkyne (like propiolic acid derivatives) to form the 1,2,3-triazole ring core of Rufinamide through Click chemistry.
The CAS number of 2,6-Difluorobenzyl chloride is 697-73-4.
The molecular formula of 2,6-Difluorobenzyl chloride is C7H5ClF2.
The listed molecular weight of 2,6-Difluorobenzyl chloride is 162.56 g/mol.
2,6-Difluorobenzyl chloride is listed as being used in connection with the following API: Rufinamide.
The listed synonym or IUPAC name for 2,6-Difluorobenzyl chloride is 2-(chloromethyl)-1,3-difluorobenzene.