2,5-Dibromopyridine

In established synthetic routes, 2,5-dibromopyridine is regioselectively converted into 2-methoxy-5-bromopyridine or similar 2-substituted-5-bromopyridine intermediates, which allows for the subsequent introduction of the required aromatic rings. 2,5-Dibromopyridine serves as a key, foundational building block in the synthesis of the antiepileptic drug Perampanel, particularly in developing the central 5-(2-pyridyl)-2-pyridone core.