2-(Propylthio)pyrimidine-4,6-diol

It typically acts as a precursor to the 5-nitro derivative, which is subsequently converted into the 4,6-dichloro intermediate used to form the core triazolopyrimidine ring system. 2-(Propylthio)pyrimidine-4,6-diol is a key early-stage intermediate in the synthesis of Ticagrelor, an antiplatelet medication marketed as Brilinta.

API Name Ticagrelor
CAS No 145783-12-6
Molecular Formula C7H10N2O2S
Molecular Weight 186.23 g/mol
Synonyms 4-hydroxy-2-propylsulfanyl-1H-pyrimidin-6-one