2-Oxo-4-phenylbutyric acid

In the production process, this compound contributes to the formation of the aromatic acyl side chain that is essential for the anticholinergic activity of the final molecule. It participates in key reaction steps leading to the development of the tropane ester framework, after which quaternization and bromide salt formation are carried out to obtain Ipratropium Bromide. Although it has no direct therapeutic activity, this intermediate has an important role in ensuring the correct structure, purity, and quality of the final API used in the management of chronic obstructive pulmonary disease (COPD) and asthma. 2-Oxo-4-phenylbutyric acid serves as an important synthetic intermediate in the manufacture of Ipratropium Bromide.

API Name Ipratropium bromide
CAS No 710-11-2
Molecular Formula C10H10O3
Molecular Weight 178.18 g/mol
Synonyms 2-oxo-4-phenylbutanoic acid