2-Methyl-5-Nitroaniline

In the synthetic route, the nitro group is typically reduced to form the corresponding phenylenediamine derivative, which then undergoes further functionalization such as acylation, urea formation, or coupling reactions to build the core diaryl thiohydantoin structure characteristic of the final molecule. The methyl substituent contributes to the correct substitution pattern required for biological activity in the finished API. 2-Methyl-5-nitroaniline is a key aromatic intermediate used in the multistep synthesis of Enzalutamide.