In the synthesis process, this compound participates in a Hantzsch-type condensation reaction with other β-ketoester and ammonia derivatives to form the 1,4-dihydropyridine ring, which is the core structural framework of Nicardipine. Thus, it acts as an important building block intermediate in the drug’s manufacturing route. 2-Methoxyethyl 2-((3-nitrophenyl)methylene)acetoacetate is a key synthetic intermediate used in the preparation of Nicardipine, a calcium channel blocker used to treat hypertension and angina.
2-Methoxyethyl 2-((3-nitrophenyl)methylene)acetoacetate
| API Name | Nicardipine |
|---|---|
| CAS No | 39562-22-6 |
| Molecular Formula | C14H15NO6 |
| Molecular Weight | 293.27 g/mol |
| Synonyms | 2-methoxyethyl (2E)-2-[(3-nitrophenyl)methylidene]-3-oxobutanoate |
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Frequently Asked Questions
In the synthesis process, this compound participates in a Hantzsch-type condensation reaction with other β-ketoester and ammonia derivatives to form the 1,4-dihydropyridine ring, which is the core structural framework of Nicardipine. Thus, it acts as an important building block intermediate in the drug’s manufacturing route. 2-Methoxyethyl 2-((3-nitrophenyl)methylene)acetoacetate is a key synthetic intermediate used in the preparation of Nicardipine, a calcium channel blocker used to treat hypertension and angina.
The CAS number of 2-Methoxyethyl 2-((3-nitrophenyl)methylene)acetoacetate is 39562-22-6.
The molecular formula of 2-Methoxyethyl 2-((3-nitrophenyl)methylene)acetoacetate is C14H15NO6.
The listed molecular weight of 2-Methoxyethyl 2-((3-nitrophenyl)methylene)acetoacetate is 293.27 g/mol.
2-Methoxyethyl 2-((3-nitrophenyl)methylene)acetoacetate is listed as being used in connection with the following API: Nicardipine.
The listed synonym or IUPAC name for 2-Methoxyethyl 2-((3-nitrophenyl)methylene)acetoacetate is 2-methoxyethyl (2E)-2-[(3-nitrophenyl)methylidene]-3-oxobutanoate.