It comprises key structural features — the biphenyl tetrazole and benzimidazole carboxylic acid core — that are elaborated in subsequent steps of the Candesartan synthesis, and is often encountered in intermediate lists for this drug substance. The compound 2‑Ethoxy‑1‑((2′‑(1‑(triphenylmethyl)‑1H‑tetrazol‑5‑yl)(1,1′‑biphenyl)‑4‑yl)methyl)‑1H‑benzimidazole‑7‑carboxylic acid serves as a synthetic intermediate in the preparation of the antihypertensive API Candesartan.
2-Ethoxy-1-((2′-(1-(triphenylmethyl)-1H-tetrazol-5-yl)(1,1′-biphenyl)-4-yl)methyl)-1H-benzimidazole-7-carboxylic acid
| API Name | Candesartan cilexetil |
|---|---|
| CAS No | 139481-72-4 |
| Molecular Formula | C43H34N6O3 |
| Molecular Weight | 682.8 g/mol |
| Synonyms | 2-ethoxy-3-[[4-[2-(1-trityltetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylic acid |
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