2-(Dimethylaminomethyl)-1-cyclohexanone hydrochloride

It is mainly used to introduce the 2-(dimethylaminomethyl)cyclohexanol structure, which is subsequently converted into the pharmacologically active trans-isomer of Tramadol. 2-(Dimethylaminomethyl)-1-cyclohexanone hydrochloride (also known as Mannich base hydrochloride or Damc) is a key intermediate in the chemical synthesis of Tramadol, a centrally acting analgesic.

API Name Tramadol
CAS No 42036-65-7
Molecular Formula C9H18ClNO
Molecular Weight 191.70 g/mol
Synonyms 2-[(dimethylamino)methyl]cyclohexan-1-one;hydrochloride

Frequently Asked Questions