In commercial and lab-scale synthesis, 2-chloropyrimidine is reacted with piperazine, typically under basic conditions, to introduce the pyrimidine ring, a core structural component of the anxiolytic drug Buspirone. 2-Chloropyrimidine is a crucial raw material in the synthesis of 1-(2-pyrimidinyl)piperazine, which serves as a key intermediate in the production of the active pharmaceutical ingredient (API) Buspirone Hydrochloride.
2-Chloropyrimidine
| API Name | Buspirone hydrochloride |
|---|---|
| CAS No | 1722-12-9 |
| Molecular Formula | C4H3ClN2 |
| Molecular Weight | 114.53 g/mol |
| Synonyms | 2-chloropyrimidine |
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Frequently Asked Questions
In commercial and lab-scale synthesis, 2-chloropyrimidine is reacted with piperazine, typically under basic conditions, to introduce the pyrimidine ring, a core structural component of the anxiolytic drug Buspirone. 2-Chloropyrimidine is a crucial raw material in the synthesis of 1-(2-pyrimidinyl)piperazine, which serves as a key intermediate in the production of the active pharmaceutical ingredient (API) Buspirone Hydrochloride.
The CAS number of 2-Chloropyrimidine is 1722-12-9.
The molecular formula of 2-Chloropyrimidine is C4H3ClN2.
The listed molecular weight of 2-Chloropyrimidine is 114.53 g/mol.
2-Chloropyrimidine is listed as being used in connection with the following API: Buspirone hydrochloride.
The listed synonym or IUPAC name for 2-Chloropyrimidine is 2-chloropyrimidine.