2-Bromo-5-fluoro-4-nitroaniline

It is specifically used to construct the fluorinated indole core of the Tezacaftor molecule. 2-Bromo-5-fluoro-4-nitroaniline is a critical intermediate in the synthesis of Tezacaftor (VX-661), a CFTR-modulator drug used to treat cystic fibrosis.

API Name Tezacaftor
CAS No 952664-69-6
Molecular Formula C6H4BrFN2O2
Molecular Weight 235.01 g/mol
Synonyms 2-bromo-5-fluoro-4-nitroaniline

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