2-Acetonyl-5,5-dimethyl-2-oxo-1,3,2-dioxaphosphorinane

The intermediate compound 2-acetonyl-5,5-dimethyl-2-oxo-1,3,2-dioxaphosphorinane is employed to synthesize the Efonidipine (also known as Efonidipine hydrochloride or EFH), a calcium-channel blocking drug used for treating hypertension and other cardiovascular disorders.

API Name Efonidipine
CAS No 111011-80-4
Molecular Formula C8H15O4P
Molecular Weight 206.18 g/mol
Synonyms 1-(5,5-dimethyl-2-oxo-1,3,2λ5-dioxaphosphinan-2-yl)propan-2-one