It serves as a penultimate precursor that reacts with 1-(2-hydroxyethyl)piperazine to introduce the piperazine side chain, completing the molecule. 2-[(6-chloro-2-methylpyrimidin-4-yl)amino]-N-(2-chloro-6-methylphenyl)-1,3-thiazole-5-carboxamide is a key intermediate in the synthesis of Dasatinib, a tyrosine kinase inhibitor.
2-[(6-chloro-2-methylpyrimidin-4-yl)amino]-N-(2-chloro-6-methylphenyl)-1,3-thiazole-5-carboxamide
| API Name | Dasatinib |
|---|---|
| CAS No | 302964-08-5 |
| Molecular Formula | C16H13Cl2N5OS |
| Molecular Weight | 394.3 g/mol |
| Synonyms | N-(2-chloro-6-methylphenyl)-2-[(6-chloro-2-methylpyrimidin-4-yl)amino]-1,3-thiazole-5-carboxamide |
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Frequently Asked Questions
It serves as a penultimate precursor that reacts with 1-(2-hydroxyethyl)piperazine to introduce the piperazine side chain, completing the molecule. 2-[(6-chloro-2-methylpyrimidin-4-yl)amino]-N-(2-chloro-6-methylphenyl)-1,3-thiazole-5-carboxamide is a key intermediate in the synthesis of Dasatinib, a tyrosine kinase inhibitor.
The CAS number of 2-[(6-chloro-2-methylpyrimidin-4-yl)amino]-N-(2-chloro-6-methylphenyl)-1,3-thiazole-5-carboxamide is 302964-08-5.
The molecular formula of 2-[(6-chloro-2-methylpyrimidin-4-yl)amino]-N-(2-chloro-6-methylphenyl)-1,3-thiazole-5-carboxamide is C16H13Cl2N5OS.
The listed molecular weight of 2-[(6-chloro-2-methylpyrimidin-4-yl)amino]-N-(2-chloro-6-methylphenyl)-1,3-thiazole-5-carboxamide is 394.3 g/mol.
2-[(6-chloro-2-methylpyrimidin-4-yl)amino]-N-(2-chloro-6-methylphenyl)-1,3-thiazole-5-carboxamide is listed as being used in connection with the following API: Dasatinib.
The listed synonym or IUPAC name for 2-[(6-chloro-2-methylpyrimidin-4-yl)amino]-N-(2-chloro-6-methylphenyl)-1,3-thiazole-5-carboxamide is N-(2-chloro-6-methylphenyl)-2-[(6-chloro-2-methylpyrimidin-4-yl)amino]-1,3-thiazole-5-carboxamide.