2-(4-Hydroxyphenyl)benzo(b)thiophen-6-ol

Raloxifene is widely used for the prevention and treatment of osteoporosis in postmenopausal women and for reducing the risk of hormone-dependent breast cancer. This intermediate contributes to forming the benzothiophene core with dual hydroxyl functional groups, which are essential for Raloxifene’s estrogen receptor binding and therapeutic activity. 2-(4-Hydroxyphenyl)benzo[b]thiophen-6-ol is an important intermediate compound employed to synthesize Raloxifene hydrochloride, a selective estrogen receptor modulator (SERM).