2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene

It is also sometimes studied for potential anticancer activity in lung cancer cells, but its primary commercial use is in the synthesis of this pharmaceutical. 2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene serves as a chemical intermediate to synthesize the antidiabetic drug canagliflozin, a type of SGLT2 inhibitor.

API Name Canagliflozin
CAS No 898566-17-1
Molecular Formula C18H14FIS
Molecular Weight 408.3 g/mol
Synonyms 2-(4-fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene