It serves as a precursor that undergoes reduction of the ketone group and hydrolysis of the methyl ester to produce Fexofenadine hydrochloride. 2-[4-[4-[4-(Hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl]phenyl]-2,2-dimethylacetic acid methyl ester is a key intermediate, often called 1-oxo fexofenadine methyl ester, employed to synthesize the antihistamine Fexofenadine.
2-[4-[4-[4-(Hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl]phenyl]-2,2-dimethylacetic acid methyl ester
| API Name | Fexofenadine |
|---|---|
| CAS No | 154477-55-1 |
| Molecular Formula | C33H39NO4 |
| Molecular Weight | 513.7 g/mol |
| Synonyms | methyl 2-[4-[4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butanoyl]phenyl]-2-methylpropanoate |
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