2-(1H-indol-5-yl)-N-methylethanesulfonamide

It acts as the indole-based precursor that undergoes subsequent functionalization, typically involving introduction of the piperidine ring at the 3-position, to produce the final drug. It is often prepared via Fischer indolization, often following decarboxylation of 5-{2-[(methylamino)sulfonyl]ethyl}-1H-indole-2-carboxylic acid. 2-(1H-indol-5-yl)-N-methylethanesulfonamide is a key intermediate in the synthesis of Naratriptan, an anti-migraine medication.