The compound is a protected precursor of Baricitinib, with the ethylsulfonyl group, the azetidine ring, the pyrrolo[3-d]pyrimidine core, and the pyrazole ring being its key structural features. This chemical name describes a synthetic intermediate used in the manufacturing of Baricitinib, a Janus kinase (JAK) inhibitor drug.
2-(1-(Ethylsulfonyl)-3-(4-(7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)azetidin-3-yl)acetonitrile
| API Name | Baricitinib |
|---|---|
| CAS No | 1187594-13-3 |
| Molecular Formula | C22H31N7O3SSi |
| Molecular Weight | 501.7 g/mol |
| Synonyms | 2-[1-ethylsulfonyl-3-[4-[7-(2-trimethylsilylethoxymethyl)pyrrolo[2,3-d]pyrimidin-4-yl]pyrazol-1-yl]azetidin-3-yl]acetonitrile |
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Frequently Asked Questions
The compound is a protected precursor of Baricitinib, with the ethylsulfonyl group, the azetidine ring, the pyrrolo[3-d]pyrimidine core, and the pyrazole ring being its key structural features. This chemical name describes a synthetic intermediate used in the manufacturing of Baricitinib, a Janus kinase (JAK) inhibitor drug.
The CAS number of 2-(1-(Ethylsulfonyl)-3-(4-(7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)azetidin-3-yl)acetonitrile is 1187594-13-3.
The molecular formula of 2-(1-(Ethylsulfonyl)-3-(4-(7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)azetidin-3-yl)acetonitrile is C22H31N7O3SSi.
The listed molecular weight of 2-(1-(Ethylsulfonyl)-3-(4-(7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)azetidin-3-yl)acetonitrile is 501.7 g/mol.
2-(1-(Ethylsulfonyl)-3-(4-(7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)azetidin-3-yl)acetonitrile is listed as being used in connection with the following API: Baricitinib.
The listed synonym or IUPAC name for 2-(1-(Ethylsulfonyl)-3-(4-(7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)azetidin-3-yl)acetonitrile is 2-[1-ethylsulfonyl-3-[4-[7-(2-trimethylsilylethoxymethyl)pyrrolo[2,3-d]pyrimidin-4-yl]pyrazol-1-yl]azetidin-3-yl]acetonitrile.