The molecule incorporates a triazolo[4,5-d]pyrimidine core, a recognized purine bioisostere, substituted with chloro and propylthio groups that enhance lipophilicity and modulate biological interaction profiles. The heterocycle is covalently attached to a cyclopentane-1,2-diol framework, serving as a carbocyclic ribose surrogate, which confers improved metabolic stability compared to natural nucleosides. A 2-hydroxyethoxy side chain further increases polarity and aqueous compatibility. (1S,2S,3R,5S)-3-(7-Chloro-5-(Propylthio)-3H-[1,2,3]Triazolo[4,5-d]Pyrimidin-3-Yl)-5-(2-Hydroxyethoxy)Cyclopentane-1,2-Diol is a synthetically complex nucleoside-analog compound featuring a triazolopyrimidine heterocycle linked to a stereochemically defined carbocyclic sugar mimic.
(1S,2S,3R,5S)-3-(7-Chloro-5-(Propylthio)-3H-[1,2,3]Triazolo[4,5-d]Pyrimidin-3-Yl)-5-(2-Hydroxyethoxy)Cyclopentane-1,2-Diol
| API Name | Ticagrelor |
|---|---|
| CAS No | 2248538-63-6 |
| Molecular Formula | C14H20ClN5O4S |
| Molecular Weight | 389.9 g/mol |
| Synonyms | (1S,2S,3R,5S)-3-(7-chloro-5-propylsulfanyltriazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol |
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Frequently Asked Questions
The molecule incorporates a triazolo[4,5-d]pyrimidine core, a recognized purine bioisostere, substituted with chloro and propylthio groups that enhance lipophilicity and modulate biological interaction profiles. The heterocycle is covalently attached to a cyclopentane-1,2-diol framework, serving as a carbocyclic ribose surrogate, which confers improved metabolic stability compared to natural nucleosides. A 2-hydroxyethoxy side chain further increases polarity and aqueous compatibility. (1S,2S,3R,5S)-3-(7-Chloro-5-(Propylthio)-3H-[1,2,3]Triazolo[4,5-d]Pyrimidin-3-Yl)-5-(2-Hydroxyethoxy)Cyclopentane-1,2-Diol is a synthetically complex nucleoside-analog compound featuring a triazolopyrimidine heterocycle linked to a stereochemically defined carbocyclic sugar mimic.
The CAS number of (1S,2S,3R,5S)-3-(7-Chloro-5-(Propylthio)-3H-[1,2,3]Triazolo[4,5-d]Pyrimidin-3-Yl)-5-(2-Hydroxyethoxy)Cyclopentane-1,2-Diol is 2248538-63-6.
The molecular formula of (1S,2S,3R,5S)-3-(7-Chloro-5-(Propylthio)-3H-[1,2,3]Triazolo[4,5-d]Pyrimidin-3-Yl)-5-(2-Hydroxyethoxy)Cyclopentane-1,2-Diol is C14H20ClN5O4S.
The listed molecular weight of (1S,2S,3R,5S)-3-(7-Chloro-5-(Propylthio)-3H-[1,2,3]Triazolo[4,5-d]Pyrimidin-3-Yl)-5-(2-Hydroxyethoxy)Cyclopentane-1,2-Diol is 389.9 g/mol.
(1S,2S,3R,5S)-3-(7-Chloro-5-(Propylthio)-3H-[1,2,3]Triazolo[4,5-d]Pyrimidin-3-Yl)-5-(2-Hydroxyethoxy)Cyclopentane-1,2-Diol is listed as being used in connection with the following API: Ticagrelor.
The listed synonym or IUPAC name for (1S,2S,3R,5S)-3-(7-Chloro-5-(Propylthio)-3H-[1,2,3]Triazolo[4,5-d]Pyrimidin-3-Yl)-5-(2-Hydroxyethoxy)Cyclopentane-1,2-Diol is (1S,2S,3R,5S)-3-(7-chloro-5-propylsulfanyltriazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol.