This specific chiral amine intermediate, often used as its N-acetyl-L-leucine salt, is a key building block to form the final active pharmaceutical ingredient (API). The compound (1S)-1-(3-Ethoxy-4-methoxy-phenyl)-2-methanesulfonyl-ethylamine is a crucial intermediate in the synthesis of Apremilast, a phosphodiesterase 4 (PDE4) inhibitor used to treat conditions like psoriatic arthritis and plaque psoriasis, working by modulating inflammatory responses.
(1S)-1-(3-Ethoxy-4-methoxy-phenyl)-2-methanesulfonyl-ethylamine
| API Name | Apremilast |
|---|---|
| CAS No | 608141-42-0 |
| Molecular Formula | C12H19NO4S |
| Molecular Weight | 273.35 g/mol |
| Synonyms | (1S)-1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethanamine |
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