It serves as the (R)-enantiomer impurity that can be resolved or converted to the required (S)-enantiomer of 1-(3-ethoxy-4-methoxyphenyl)-2-methanesulfonyl-ethylamine, which is then reacted with 3-acetamidophthalic anhydride to produce Apremilast. (1R)-1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethanamine is a chiral intermediate mainly employed to synthesize Apremilast, a medication for psoriatic arthritis.
(1R)-1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethanamine
| API Name | Apremilast |
|---|---|
| CAS No | 608142-27-4 |
| Molecular Formula | C12H19NO4S |
| Molecular Weight | 273.35 g/mol |
| Synonyms | (1R)-1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethanamine |
Zoho Contact Form - Pharma Intermediates
"*" indicates required fields
Frequently Asked Questions
It serves as the (R)-enantiomer impurity that can be resolved or converted to the required (S)-enantiomer of 1-(3-ethoxy-4-methoxyphenyl)-2-methanesulfonyl-ethylamine, which is then reacted with 3-acetamidophthalic anhydride to produce Apremilast. (1R)-1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethanamine is a chiral intermediate mainly employed to synthesize Apremilast, a medication for psoriatic arthritis.
The CAS number of (1R)-1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethanamine is 608142-27-4.
The molecular formula of (1R)-1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethanamine is C12H19NO4S.
The listed molecular weight of (1R)-1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethanamine is 273.35 g/mol.
(1R)-1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethanamine is listed as being used in connection with the following API: Apremilast.
The listed synonym or IUPAC name for (1R)-1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethanamine is (1R)-1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethanamine.