1H-Pyrazole, 4-chloro

In the synthesis of lesopitron (chemically 2-{4-[4-(4-chloro-1H-pyrazol-1-yl)butyl]piperazin-1-yl}pyrimidine), 4-chloro-1H-pyrazole is typically utilized in an N-alkylation reaction to introduce the chloro-substituted pyrazole core. 4-Chloro-1H-pyrazole (CAS 15878-00-9) is a vital building block in the synthesis of lesopitron (also known as E-4424), a 5-HT1A receptor agonist developed by Esteve as an anxiolytic.