LR-103 is a naturally occurring D-hormone that is produced by the kidneys from vitamin D. LR-103 is one of the D-hormones produced from Hectorol. It is developed for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease (CKD). Studies have shown LR-103 has the same potency as calcitriol, but much lower toxicity. The directory classifies it as a preclinical API with a semi-synthetic source/manufacturing origin. Other names for this substance include LR-103, 1.alpha. and 24(S)-Dihydroxyergocalciferol. Its PubChem CID is 9547261.
1alpha,24S-Dihydroxyvitamin D2
| CAS No | 156316-85-7 |
|---|---|
| Molecular Formula | C28H44O3 |
| Molecular Weight | 428.6 g/mol |
| Synonyms | trans-(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(E,2R,5S)-5-hydroxy-5,6-dimethylhept-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol |
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LR-103 is a naturally occurring D-hormone that is produced by the kidneys from vitamin D. LR-103 is one of the D-hormones produced from Hectorol. It is developed for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease (CKD).
The listed CAS number is 156316-85-7.
The listed molecular formula is C28H44O3.
The listed molecular weight is 428.6 g/mol.
trans-(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(E,2R,5S)-5-hydroxy-5,6-dimethylhept-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol.
The source lists LR-103, 1.alpha. and 24(S)-Dihydroxyergocalciferol.