It provides the essential stereochemically defined backbone required for the drug’s biological activity, particularly contributing to the correct spatial arrangement of the amine and hydroxyl functional groups. During synthesis, this intermediate undergoes further functional group modifications and coupling steps to construct the final eliglustat molecule, which is then converted into its tartrate salt form to improve stability and bioavailability. The compound 1-Pyrrolidinepropanol, α-(2,3-dihydro-1,4-benzodioxin-6-yl)-β-[[(1S)-2-hydroxy-1-phenylethyl]amino]-, (αR,βR) serves as a key chiral intermediate in the synthesis of eliglustat tartrate.
1-Pyrrolidinepropanol, alpha-(2,3-dihydro-1,4-benzodioxin-6-yl)-beta-[[(1S)-2-hydroxy-1-phenylethyl]amino]-, (alphaR,betaR)
| API Name | Eliglustat tartrate |
|---|---|
| CAS No | 491833-27-3 |
| Molecular Formula | C23H30N2O4 |
| Molecular Weight | 398.5 g/mol |
| Synonyms | 1-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[(2-hydroxy-1-phenylethyl)amino]-3-pyrrolidin-1-ylpropan-1-ol |
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Frequently Asked Questions
It provides the essential stereochemically defined backbone required for the drug’s biological activity, particularly contributing to the correct spatial arrangement of the amine and hydroxyl functional groups. During synthesis, this intermediate undergoes further functional group modifications and coupling steps to construct the final eliglustat molecule, which is then converted into its tartrate salt form to improve stability and bioavailability. The compound 1-Pyrrolidinepropanol, α-(2,3-dihydro-1,4-benzodioxin-6-yl)-β-[[(1S)-2-hydroxy-1-phenylethyl]amino]-, (αR,βR) serves as a key chiral intermediate in the synthesis of eliglustat tartrate.
The CAS number of 1-Pyrrolidinepropanol, alpha-(2,3-dihydro-1,4-benzodioxin-6-yl)-beta-[[(1S)-2-hydroxy-1-phenylethyl]amino]-, (alphaR,betaR) is 491833-27-3.
The molecular formula of 1-Pyrrolidinepropanol, alpha-(2,3-dihydro-1,4-benzodioxin-6-yl)-beta-[[(1S)-2-hydroxy-1-phenylethyl]amino]-, (alphaR,betaR) is C23H30N2O4.
The listed molecular weight of 1-Pyrrolidinepropanol, alpha-(2,3-dihydro-1,4-benzodioxin-6-yl)-beta-[[(1S)-2-hydroxy-1-phenylethyl]amino]-, (alphaR,betaR) is 398.5 g/mol.
1-Pyrrolidinepropanol, alpha-(2,3-dihydro-1,4-benzodioxin-6-yl)-beta-[[(1S)-2-hydroxy-1-phenylethyl]amino]-, (alphaR,betaR) is listed as being used in connection with the following API: Eliglustat tartrate.
The listed synonym or IUPAC name for 1-Pyrrolidinepropanol, alpha-(2,3-dihydro-1,4-benzodioxin-6-yl)-beta-[[(1S)-2-hydroxy-1-phenylethyl]amino]-, (alphaR,betaR) is 1-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[(2-hydroxy-1-phenylethyl)amino]-3-pyrrolidin-1-ylpropan-1-ol.