1-Oxo-2,3-Dihydro-1H-Indene-4-Carbonitrile

It is mainly used to introduce the indane core by forming an (S)-4-cyano-1-aminoindane intermediate, a critical chiral component of the API (active pharmaceutical ingredient) used for multiple sclerosis. 1-Oxo-2,3-dihydro-1H-indene-4-carbonitrile (also known as 4-cyano-1-indanone) is a key starting material in the synthesis of Ozanimod hydrochloride.

API Name Ozanimod hydrochloride
CAS No 60899-34-5
Molecular Formula C10H7NO
Molecular Weight 157.17 g/mol
Synonyms 1-oxo-2,3-dihydroindene-4-carbonitrile