1-Benzyl-N,4-dimethyl-piperidin-3-amine dihydrochloride, (3R,4R)

It is also broadly used as a pharmaceutical intermediate in the research and development of other Janus kinase inhibitors and various chemical production processes. (3R,4R)-1-Benzyl-N,4-dimethyl-piperidin-3-amine dihydrochloride is used mainly as a key intermediate in the synthesis of the drug Tofacitinib, which treats autoimmune diseases like rheumatoid arthritis.

API Name Tofacitinib
CAS No 1062580-52-2
Molecular Formula C14H24Cl2N2
Molecular Weight 291.3 g/mol
Synonyms (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3-amine;dihydrochloride