1-(3-Ethoxy-4-methoxy-phenyl)-2-methanesulfonyl-ethylamine

This specific amine is crucial for forming the core structure of Apremilast, also known as Otezla. The compound 1-(3-Ethoxy-4-methoxy-phenyl)-2-methanesulfonyl-ethylamine (specifically its (S)-enantiomer) is a key intermediate in the synthesis of Apremilast, a phosphodiesterase 4 (PDE4) inhibitor used to treat inflammatory conditions like psoriatic arthritis and plaque psoriasis.

API Name Apremilast
CAS No 253168-94-4
Molecular Formula C12H19NO4S
Molecular Weight 273.35 g/mol
Synonyms 1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethanamine

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