It’s a key building block in creating the complex thienopyrimidine structure of Relugolix. The compound 1-[(2,6-Difluorophenyl)methyl]-5-[(dimethylamino)methyl]-3-(6-methoxypyridazin-3-yl)-6-(4-nitrophenyl)thieno[2,3-d]pyrimidine-2,4-dione is a precursor or intermediate employed to synthesize Relugolix, a GnRH antagonist, in which the nitro group on the phenyl ring is typically modified (e.g., reduced to an amine, then reacted to form a urea) to form the final active drug.
1-[(2,6-Difluorophenyl)methyl]-5-[(dimethylamino)methyl]-3-(6-methoxypyridazin-3-yl)-6-(4-nitrophenyl)thieno[2,3-d]pyrimidine-2,4-dione
| API Name | Relugolix |
|---|---|
| CAS No | 1589503-96-7 |
| Molecular Formula | C27H22F2N6O5S |
| Molecular Weight | 580.6 g/mol |
| Synonyms | 1-[(2,6-difluorophenyl)methyl]-5-[(dimethylamino)methyl]-3-(6-methoxypyridazin-3-yl)-6-(4-nitrophenyl)thieno[2,3-d]pyrimidine-2,4-dione |
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Frequently Asked Questions
It's a key building block in creating the complex thienopyrimidine structure of Relugolix. The compound 1-[(2,6-Difluorophenyl)methyl]-5-[(dimethylamino)methyl]-3-(6-methoxypyridazin-3-yl)-6-(4-nitrophenyl)thieno[2,3-d]pyrimidine-2,4-dione is a precursor or intermediate employed to synthesize Relugolix, a GnRH antagonist, in which the nitro group on the phenyl ring is typically modified (e.g., reduced to an amine, then reacted to form a urea) to form the final active drug.
The CAS number of 1-[(2,6-Difluorophenyl)methyl]-5-[(dimethylamino)methyl]-3-(6-methoxypyridazin-3-yl)-6-(4-nitrophenyl)thieno[2,3-d]pyrimidine-2,4-dione is 1589503-96-7.
The molecular formula of 1-[(2,6-Difluorophenyl)methyl]-5-[(dimethylamino)methyl]-3-(6-methoxypyridazin-3-yl)-6-(4-nitrophenyl)thieno[2,3-d]pyrimidine-2,4-dione is C27H22F2N6O5S.
The listed molecular weight of 1-[(2,6-Difluorophenyl)methyl]-5-[(dimethylamino)methyl]-3-(6-methoxypyridazin-3-yl)-6-(4-nitrophenyl)thieno[2,3-d]pyrimidine-2,4-dione is 580.6 g/mol.
1-[(2,6-Difluorophenyl)methyl]-5-[(dimethylamino)methyl]-3-(6-methoxypyridazin-3-yl)-6-(4-nitrophenyl)thieno[2,3-d]pyrimidine-2,4-dione is listed as being used in connection with the following API: Relugolix.
The listed synonym or IUPAC name for 1-[(2,6-Difluorophenyl)methyl]-5-[(dimethylamino)methyl]-3-(6-methoxypyridazin-3-yl)-6-(4-nitrophenyl)thieno[2,3-d]pyrimidine-2,4-dione is 1-[(2,6-difluorophenyl)methyl]-5-[(dimethylamino)methyl]-3-(6-methoxypyridazin-3-yl)-6-(4-nitrophenyl)thieno[2,3-d]pyrimidine-2,4-dione.