It is coupled with a substituted indole amine, forming the central carboxamide structure of this CFTR corrector used for cystic fibrosis. 1-(2,2-Difluoro-1,3-benzodioxol-5-yl)cyclopropanecarboxylic acid is a key intermediate in the synthesis of Tezacaftor (VX-661), acting as the acyl component in the formation of the amide bond.
1-(2,2-Difluoro-1,3-benzodioxol-5-yl)cyclopropanecarboxylic acid
| API Name | Tezacaftor |
|---|---|
| CAS No | 862574-88-7 |
| Molecular Formula | C11H8F2O4 |
| Molecular Weight | 242.17 g/mol |
| Synonyms | 1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropane-1-carboxylic acid |
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Frequently Asked Questions
It is coupled with a substituted indole amine, forming the central carboxamide structure of this CFTR corrector used for cystic fibrosis. 1-(2,2-Difluoro-1,3-benzodioxol-5-yl)cyclopropanecarboxylic acid is a key intermediate in the synthesis of Tezacaftor (VX-661), acting as the acyl component in the formation of the amide bond.
The CAS number of 1-(2,2-Difluoro-1,3-benzodioxol-5-yl)cyclopropanecarboxylic acid is 862574-88-7.
The molecular formula of 1-(2,2-Difluoro-1,3-benzodioxol-5-yl)cyclopropanecarboxylic acid is C11H8F2O4.
The listed molecular weight of 1-(2,2-Difluoro-1,3-benzodioxol-5-yl)cyclopropanecarboxylic acid is 242.17 g/mol.
1-(2,2-Difluoro-1,3-benzodioxol-5-yl)cyclopropanecarboxylic acid is listed as being used in connection with the following API: Tezacaftor.
The listed synonym or IUPAC name for 1-(2,2-Difluoro-1,3-benzodioxol-5-yl)cyclopropanecarboxylic acid is 1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropane-1-carboxylic acid.