1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-(1-((2R)-2,3-dihydroxypropyl)-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl)cyclopropanecarboxamide

It is frequently formed by coupling a protected amino-indole with 1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropanecarbonyl chloride. 1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-(1-((2R)-2,3-dihydroxypropyl)-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl)cyclopropanecarboxamide is a key intermediate or a precursor to Tezacaftor (VX-661), a pharmaceutical drug used to treat cystic fibrosis, often produced in the final stages of its synthesis.