Nedocromil sodium

Nedocromil Sodium is the sodium salt form of nedocromil, a pyranoquinolone derivative with anti-inflammatory properties. Nedocromil sodium inhibits the activation and release of inflammatory mediators (leukotrienes, histamine and prostaglandins) from a variety of cells involved in hypersensitivity reactions, including mast cells, eosinophils, neutrophils, macrophages, monocytes and platelets. As a result, nedocromil sodium inhibits both immediate and late bronchoconstriction, decreases bronchial hyperresponsiveness and inhibits recruitment of other inflammatory cells into the airway epithelium. Its therapeutic use is listed as anti-asthmatic agents and ophthalmic agents. The directory classifies it as a discontinued API with a synthetic source/manufacturing origin. Other names for this substance include Tilade and Alocril. Its PubChem CID is 50295.

CAS No 69049-74-7
Molecular Formula C19H15NNa2O7
Molecular Weight 415.3 g/mol
Synonyms disodium;9-ethyl-4,6-dioxo-10-propylpyrano[3,2-g]quinoline-2,8-dicarboxylate

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