Trimethobenzamide

Trimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. Its actions are unclear but most likely involves the chemoreceptor trigger zone (CTZ). In dogs pretreated with trimethobenzamide HCl, the emetic response to apomorphine is inhibited, while little or no protection is afforded against emesis induced by intragastric copper sulfate. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Ametik damla, Tebamide, Tribenzagan, Benzacot and emedur. Its PubChem CID is 5577.

CAS No 138-56-7
Molecular Formula C21H28N2O5
Molecular Weight 388.5 g/mol
Synonyms N-[[4-[2-(dimethylamino)ethoxy]phenyl]methyl]-3,4,5-trimethoxybenzamide

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