Everolimus

Everolimus is a macrocyclic lactone that is rapamycin in which the hydroxy group attached to the cyclohexyl moiety has been converted into the corresponding 2-hydroxyethyl ether. It is an immunosuppressant and antineoplastic agent. Among its listed roles, it functions as a antineoplastic agent, an immunosuppressive agent, a mTOR inhibitor, an anticoronaviral agent and a geroprotector. It is a primary alcohol, a secondary alcohol, an ether, a cyclic ketone, a cyclic acetal and a macrolide lactam. Functionally, it is related to member of sirolimus. It is grouped under the following drug class(es): Immunosuppressants and Kinase inhibitors. Its therapeutic use is listed as anti-cancer agents, anti-epileptic drugs, antineoplastics and central nervous system (CNS) agents. The directory classifies it as a commercial API with a semi-synthetic source/manufacturing origin. Other names for this substance include Zortress, Afinitor and Certican. Its PubChem CID is 6442177.

CAS No 159351-69-6
Molecular Formula C53H83NO14
Molecular Weight 958.2 g/mol
Synonyms (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl]-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone

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