Estradiol hemisuccinate is mainly used in Hormone Replacement Therapy (HRT) for menopausal symptoms like hot flashes, night sweats, and vaginal atrophy, helping with estrogen deficiency and preventing postmenopausal osteoporosis. It’s also used for hypoestrogenism, supports skin health, and, in combination with progesterone, can induce withdrawal bleeding for amenorrhea. It is grouped under the following drug class(es): Steroids. Its therapeutic use is listed as anti-osteoporosis agents. The directory classifies it as a commercial API with a semi-synthetic source/manufacturing origin. Other names for this substance include Estradiol 17β-hemisuccinate and β-Estradiol-17β-hemisuccinate. It is also listed for alternate use as: API Intermediate. Its PubChem CID is 66440.
Estradiol hemisuccinate
| CAS No | 7698-93-3 |
|---|---|
| Molecular Formula | C22H28O5 |
| Molecular Weight | 372.5 g/mol |
| Synonyms | 4-[[(8R,9S,13S,14S,17S)-3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]oxy]-4-oxobutanoic acid |
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Frequently Asked Questions
Estradiol hemisuccinate is mainly used in Hormone Replacement Therapy (HRT) for menopausal symptoms like hot flashes, night sweats, and vaginal atrophy, helping with estrogen deficiency and preventing postmenopausal osteoporosis.
The listed CAS number is 7698-93-3.
The listed molecular formula is C22H28O5.
The listed molecular weight is 372.5 g/mol.
4-[[(8R,9S,13S,14S,17S)-3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]oxy]-4-oxobutanoic acid.
The source lists Estradiol 17β-hemisuccinate and β-Estradiol-17β-hemisuccinate.