Enalaprilat (anhydrous) is enalapril in which the ethyl ester group has been hydrolysed to the corresponding carboxylic acid. Enalaprilat is an angiotensin-converting enzyme (ACE) inhibitor and is used (often in the form of its prodrug, enalapril) in the treatment of hypertension and heart failure, for reduction of proteinuria and renal disease in patients with nephropathies, and for the prevention of stroke, myocardial infarction, and cardiac death in high-risk patients. Unlike enalapril, enalaprilat is not absorbed by mouth but is given by intravenous injection, usually as the dihydrate. Among its listed roles, it functions as a EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor and an antihypertensive agent. It is a dicarboxylic acid and a dipeptide. It is grouped under the following drug class(es): ACE Inhibitors. Its therapeutic use is listed as antihypertensives and cardiovascular. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Enalaprilat anhydrous, Enalaprilate and Enalaprilatum. Its PubChem CID is 5462501.
Enalaprilat
| CAS No | 76420-72-9 |
|---|---|
| Molecular Formula | C18H24N2O5 |
| Molecular Weight | 348.4 g/mol |
| Synonyms | (2S)-1-[(2S)-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]propanoyl]pyrrolidine-2-carboxylic acid |
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Frequently Asked Questions
Enalaprilat (anhydrous) is enalapril in which the ethyl ester group has been hydrolysed to the corresponding carboxylic acid.
The listed CAS number is 76420-72-9.
The listed molecular formula is C18H24N2O5.
The listed molecular weight is 348.4 g/mol.
(2S)-1-[(2S)-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]propanoyl]pyrrolidine-2-carboxylic acid.
The source lists Enalaprilat anhydrous, Enalaprilate and Enalaprilatum.