Diquafosol is a synthetic purinergic P2Y₂ receptor agonist used as an Active Pharmaceutical Ingredient (API) in ophthalmic preparations for the treatment of dry eye disease.Diquafosol acts by stimulating P2Y₂ receptors on the ocular surface and conjunctival epithelial cells. This stimulation enhances aqueous tear secretion and mucin production, improving tear film stability and ocular surface hydration. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Diquafosolum and Dicuafosol. Its PubChem CID is 148197.
Diquafosol
| CAS No | 59985-21-6 |
|---|---|
| Molecular Formula | C18H26N4O23P4 |
| Molecular Weight | 790.3 g/mol |
| Synonyms | [[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] hydrogen phosphate |
Zoho Contact Form
"*" indicates required fields
Frequently Asked Questions
Diquafosol acts by stimulating P2Y₂ receptors on the ocular surface and conjunctival epithelial cells. This stimulation enhances aqueous tear secretion and mucin production, improving tear film stability and ocular surface hydration.
The listed CAS number is 59985-21-6.
The listed molecular formula is C18H26N4O23P4.
The listed molecular weight is 790.3 g/mol.
[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] hydrogen phosphate.
The source lists Diquafosolum and Dicuafosol.