Diisopropyl fluorophosphate

Isofluorphate appears as oily liquid. Clear, colorless or faintly yellow liquid. This material is used as a research tool in neuroscience for its ability to inhibit cholinesterase (by phosphorylation) on an acute/sub-acute basis and to produce a delayed neuropathy. An insecticide. Used in Germany as a basis for “nerve gases”. An irreversible cholinesterase inhibitor with actions similar to those of echothiophate. It is a powerful miotic used mainly in the treatment of glaucoma. Its vapor is highly toxic and it is recommended that only solutions in arachis oil be used therapeutically. The directory classifies it as a discontinued API with a synthetic source/manufacturing origin. Other names for this substance include Isoflurophate, Diflupyl and Neoglaucit. It is also listed for alternate use as: API Impurity. Its PubChem CID is 5936.

CAS No 55-91-4
Molecular Formula C6H14FO3P
Molecular Weight 184.15 g/mol
Synonyms 2-[fluoro(propan-2-yloxy)phosphoryl]oxypropane

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