Dexamethasone

Dexamethasone is a fluorinated steroid that is 9-fluoropregna-1,4-diene substituted by hydroxy groups at positions 11, 17 and 21, a methyl group at position 16 and oxo groups at positions 3 and 20. It is a synthetic member of the class of glucocorticoids. Among its listed roles, it functions as a adrenergic agent, an antiemetic, an antineoplastic agent, an environmental contaminant, a xenobiotic, an immunosuppressive agent and an anti-inflammatory drug. It is grouped under the following drug class(es): Antiemetics, Corticosteroids, Immunosuppressants, Ophthalmic corticosteroids, Steroids and Systemic corticosteroids. Its therapeutic use is listed as adhesion-prevention agents, anti-asthmatic agents, anti-inflammatories, antirheumatic agents, ophthalmic agents and osteoarthritis agents. The directory classifies it as a commercial API with a semi-synthetic source/manufacturing origin. Other names for this substance include Decadron, DexPak, Fluormethylprednisolone, Superprednol, Visumetazone and Cortisumman. Its PubChem CID is 5743.

CAS No 50-02-2
Molecular Formula C22H29FO5
Molecular Weight 392.5 g/mol
Synonyms (8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one

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